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The Effect of the Clenbuterol—β۲-Adrenergic Receptor Agonist on the Peripheral Blood Mononuclear Cells Proliferation, Phenotype, Functions, and Reactive Oxygen Species Production in Race Horses In Vitro O. Pingwara, +1 author A. Winnicka Published 1 April 2021 Biology Cells. Case description: 3 Quarter Horse racehorses were examined for suspected clenbuterol overdose 12 to 24 hours after administration by mouth of a compounded clenbuterol product. Clinical findings: All horses developed sinus tachycardia, muscle tremors, hyperhidrosis, and colic. Clenbuterol is the only Food and Drug Administration approved bronchodilator, but published research evidence regarding efficacy is equivocal. There is documented evidence that clenbuterol has been routinely administered absent any medical indication to racehorses, likely due to the increase in muscle mass associated with leptin- and adiponectin-mediated repartitioning effects. On May 25, 2021, at its monthly public meeting and in accordance with its statutory authority the Commission approved the above ARCI amendment prohibiting the use of Clenbuterol in thoroughbred race horses except with enumerated conditions. This amendment shall take effect on July 1 9, 2021. Examples of controlled medications include acepromazine, carprofen, clenbuterol (Ventipulmin), diclofenac (Surpass), detomidine, DMSO, firocoxib (Equioxx), flunixin (Banamine), lidocaine, isoxuprine, pergolide, phenylbutazone, and tiludronic acid (Tildren). As with the examples of banned substances, this list is nowhere near complete Our Clenbuterol is 100% genuine and comes with a guarantee of purity, so you can be sure you’re not wasting your money on a counterfeit product, clenbuterol in racehorses.
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